Carboxy-PEG4-phosphonic acid
This product is a heterobifunctional PEG linker containing a carboxyl group, a PEG4 spacer, and a phosphonic acid. It specifically enables amide coupling and surface modification, providing solubility, dual reactivity, and charged functionality for bioconjugation and material science.
Key Features and Benefits
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Carboxyl Group: Couples efficiently with primary amines to form stable amide bonds.
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Phosphonic Acid: Provides strong chelation and surface-binding capability.
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PEG4 Spacer: Enhances solubility and provides moderate chain length.
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Dual Reactivity: Combines carboxyl conjugation with phosphonic functionality.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Links biomolecules via amide chemistry while introducing phosphonic groups.
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Surface Modification: Functionalizes metal oxides, nanoparticles, and polymers.
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Probe Development: Builds multifunctional probes with orthogonal handles.
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Drug Delivery: Provides PEG scaffolds with solubility and charged functionality.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Dissolve in aqueous buffers or polar solvents; avoid prolonged exposure to moisture.
This product integrates carboxyl conjugation with phosphonic chemistry in a PEG4 scaffold, specifically offering solubility, dual reactivity, and strong surface affinity.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.