Carboxy-PEG4-phosphonic acid ethyl ester contains a carboxylic acid end group and a phosphonic acid ethyl ester moiety. The carboxylic acid can react with primary amines in the presence of coupling reagents, such as ,EDC, HATU and DCC, to form stable amide bonds. Phosphonic acid is used for surface modification. The hydrophilic PEG linker can increase the solubility of a compound in aqueous media and improve the hydrophilicity of the surfaces.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.