N-Fmoc-N’-(azido-PEG4)-L-Lysine- PFP ester

N-Fmoc-N’-(azido-PEG4)-L-Lysine- PFP ester is a crosslinker containing one Fmoc protected amine, an azide group and a lysine. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to afford a stable triazole linkage. The PEG spacer increases the aqueous solubility of the resulting compound. It can be used in the synthesis of PROTACs.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.