Bis-PE21-NHS ester
This product is a homobifunctional PEG-based crosslinker featuring two NHS ester groups separated by a long PEG21 spacer. This design provides excellent solubility, flexibility, and extended spacing, making it especially effective for protein crosslinking, bioconjugation, and surface functionalization.
Key Features and Benefits:
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Dual NHS Esters: Efficiently couple with primary amines under mild conditions.
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PEG21 Spacer: Enhances solubility, flexibility, and steric accessibility.
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Extended Length: Provides optimal spacing for large biomolecules.
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Symmetric Design: Ideal for homobifunctional conjugation.
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High Purity: Ensures reproducible results in advanced workflows.
Applications:
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Protein Crosslinking: Links amine-containing biomolecules for structural studies.
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Bioconjugation: Supports multifunctional and symmetric conjugates.
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Drug Delivery: Provides PEGylated scaffolds with stable amide bonds.
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Surface Functionalization: Introduces amine-reactive handles to polymers and nanoparticles.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); prepare fresh solutions to avoid NHS hydrolysis.
This product combines dual amine-reactivity with long PEG spacing, offering solubility and control specifically for advanced conjugation and crosslinking strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.