Bis-PEG7-NHS ester CAS:1334170-02-3 is a high-performance, biocompatible, and water-soluble crosslinking reagent. Comprising two functional groups, N-hydroxysuccinimide (NHS) ester and polyethylene glycol (PEG), it offers remarkable versatility in pharmaceutical research and development.
The NHS ester group selectively reacts with primary amines found in proteins, peptides, and other biomolecules to form stable amide bonds. The PEG moiety imparts enhanced water solubility, reduced immunogenicity, and improved biocompatibility to conjugated molecules. The 7-unit PEG chain offers optimal spacer length for various applications, including drug delivery, protein modification, and bioconjugation.
Bis-PEG7-NHS ester is employed in the development of targeted therapeutics, diagnostics, and imaging agents. Its ability to crosslink multiple biomolecules enables researchers to design multifunctional constructs, such as antibody-drug conjugates and protein-polymer conjugates, with improved pharmacokinetic properties and targeted delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
