Mal-amido-PEG9-NH-Boc
This product is a heterobifunctional PEG linker featuring a maleimide group for thiol-specific conjugation and a Boc-protected amine for orthogonal synthesis. The PEG9 spacer provides solubility, flexibility, and spacing, making it especially ideal for controlled bioconjugation, drug delivery, and multifunctional probe development.
Key Features and Benefits:
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Maleimide Group: Reacts selectively with thiols to form stable thioether bonds.
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Boc-Protected Amine: Acid-labile protection enables orthogonal conjugation.
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PEG9 Spacer: Improves solubility, hydrophilicity, and steric accessibility.
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Dual Functionality: Supports thiol conjugation and orthogonal synthesis strategies.
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High Purity: Ensures reproducibility in advanced workflows.
Applications:
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Bioconjugation: Couples thiol-containing biomolecules with controlled protection.
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Drug Delivery: Provides PEGylated scaffolds with orthogonal handles for targeted release.
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Probe Development: Builds multifunctional imaging and diagnostic probes.
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Synthetic Chemistry: Serves as an intermediate for orthogonal linker assembly.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF); avoid premature Boc deprotection.
This product combines thiol-specific maleimide chemistry with Boc-protected amine orthogonality in a PEG9 scaffold, specifically offering versatility for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
