3-(m-PEG12-ethoxycarbonyl)propanoic acid
This product is a PEG12-based linker with a terminal methoxy group on one end and a carboxylic acid on the other, connected through an ethoxycarbonyl-propanoic backbone. The PEG12 spacer imparts excellent hydrophilicity, flexibility, and long spacing, making this compound especially suitable for bioconjugation, drug delivery, and surface engineering.
Key Features and Benefits:
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Carboxylic Acid Group: Couples efficiently with amines for stable amide bond formation.
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Methoxy-Terminated PEG Chain: Provides non-reactive end capping, enhancing stability and solubility.
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PEG12 Spacer: Ensures long hydrophilic spacing, steric accessibility, and reduced aggregation.
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High Purity: Delivers reproducibility in sensitive conjugation workflows.
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Versatile Design: Useful for biomolecule modification and material functionalization.
Applications:
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Bioconjugation: Introduces PEG spacing in protein, peptide, or small-molecule conjugates.
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Drug Delivery: PEGylated linker improves solubility, stability, and circulation time.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
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Material Science: Useful in scaffold design and biomaterial engineering.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain acid stability.
This product offers long PEG spacing with a carboxyl group for amide coupling, making it an especially versatile reagent for advanced conjugation and material modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
