Azido-PEG3-(CH2)3OH CAS:1807512-36-2 is a highly versatile polyethylene glycol (PEG) derivative that offers exceptional functionality in pharmaceutical research and development. This compound features an azido group (N3) at one end, which is recognized for its high reactivity in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC). These click chemistry reactions enable the formation of stable, covalent linkages with minimal side reactions, making azido-functionalized PEGs ideal for advanced bioconjugation strategies.
The PEG3 linker, a triethylene glycol, serves as a biocompatible, flexible spacer that imparts beneficial properties, such as increased solubility, reduced immunogenicity, and improved pharmacokinetic profiles. At the other end, the compound features a hydroxyl (OH) group, offering further reactivity and the potential for additional chemical modifications.
Azido-PEG3-(CH2)3OH is well-suited for a wide array of applications in pharmaceutical research and development. These applications include the synthesis of targeted drug conjugates, PEGylation of proteins and peptides, and the development of advanced drug delivery systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
