Fmoc-NMe-PEG4-acid
This product is a PEG linker containing an N-methyl Fmoc-protected amine, a PEG4 spacer, and a terminal carboxylic acid. It specifically enables orthogonal protection, controlled deprotection, and versatile coupling for bioconjugation and synthetic applications.
Key Features and Benefits
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N-methyl Fmoc Group: Provides orthogonal protection with selective deprotection options.
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Carboxylic Acid: Couples efficiently with amines to form stable amide bonds.
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PEG4 Spacer: Enhances solubility and reduces steric hindrance.
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Dual Reactivity: Combines amine protection with carboxyl conjugation.
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High Purity: Ensures reproducibility in synthetic and bioconjugation workflows.
Applications
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Bioconjugation: Links PEG chains to biomolecules with orthogonal control.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEG scaffolds with dual functionality for therapeutic designs.
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Organic Synthesis: Serves as a versatile intermediate in linker chemistry.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain stability.
This product integrates N-methyl Fmoc-protected amine chemistry with carboxyl functionality in a PEG4 scaffold, specifically offering controlled reactivity for conjugation and synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
