PC-Biotin-PEG4-PEG3-azide
This product is a multifunctional linker combining a photocleavable (PC) group with biotin for avidin binding and a terminal azide specifically for click chemistry. The PEG4-PEG3 spacers provide solubility, flexibility, and spacing, making it especially ideal for photocontrolled bioconjugation, probe development, and targeted release.
Key Features and Benefits:
-
Photocleavable Group: Enables light-triggered release of conjugates.
-
Biotin Moiety: Provides strong avidin/streptavidin binding for detection and enrichment.
-
Azide Group: Supports CuAAC or SPAAC click chemistry with alkynes.
-
PEG Spacers: Enhance solubility, hydrophilicity, and steric accessibility.
-
High Purity: Ensures reproducibility in sensitive workflows.
Applications:
-
Photocontrolled Bioconjugation: Allows spatiotemporal release of biomolecules.
-
Probe Development: Builds light-responsive, biotinylated probes for imaging and diagnostics.
-
Drug Delivery: Supports photocaged PEGylated scaffolds for targeted therapy.
-
Bioconjugation: Combines biotin capture, click chemistry, and photocleavage.
Storage and Handling:
-
Storage: Store at –20 °C in a tightly sealed, light- and moisture-protected container.
-
Handling: Protect from light exposure to prevent premature photocleavage.
This product integrates photocleavable biotin with azide reactivity and PEG spacing, specifically enabling light-controlled conjugation and multifunctional applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
