Folate PEG linker serves as an excellent target oriented molecular probe. Folic acid PEG linkers have improved aqueous solubility compared to their non-PEG versions. Azide moiety is widely tolerated in biological systems with minimal inteference to their activities. It readily reacts with alkyne-labeled biomolecules via click chemistry. They have been widely used in target drug delivery and MRI imaging applications.The PEG spacer increase the solubility of the resulting complex in aqueous media.
Folate PEG linker serves as an excellent target oriented molecular probe. Folic acid PEG linkers have improved aqueous solubility compared to their non-PEG versions. Azide moiety is widely tolerated in biological systems with minimal inteference to their activities. It readily reacts with alkyne-labeled biomolecules via click chemistry. They have been widely used in target drug delivery and MRI imaging applications.The PEG spacer increase the solubility of the resulting complex in aqueous media.
Folate-PEG2-Azide contains an azide functional group (-N3) attached to the end of a PEG chain, which is conjugated with folate, a vitamin B9-derived molecule that binds specifically to folate receptors overexpressed on certain cancer cells.
The azide group is known for its ability to react with other molecules through click chemistry, which makes Folate-PEG2-Azide a useful tool in the field of pharmaceutical research and development. Click chemistry tools are a powerful bioconjugation technique that allows for rapid and efficient covalent attachment of different molecules, such as drugs or imaging agents, to the PEG chain via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
