Phthalimidoxy-PEG1-acid

Phthalimidoxy-PEG1-acid

This product is a heterobifunctional PEG linker containing a phthalimidoxy protecting group, a PEG1 spacer, and a terminal carboxylic acid. It specifically enables protecting group strategies, amide coupling, and conjugation, offering solubility and compact structure.

Key Features and Benefits

• Phthalimidoxy Group: Provides stability and controlled deprotection for orthogonal chemistry.

• Carboxylic Acid: Couples efficiently with amines to form stable amide bonds.

• PEG1 Spacer: Offers compact solubility and low steric hindrance.

• Versatile Reactivity: Combines protecting group chemistry with carboxyl functionality.

• High Purity: Ensures reproducibility in synthesis and conjugation workflows.

Applications

• Bioconjugation: Links biomolecules through amide bond formation.

• Protecting Group Strategies: Enables staged reactivity in synthetic workflows.

• Probe Development: Serves as an intermediate for multifunctional probe design.

• Medicinal Chemistry: Supports drug design and linker development.

Storage and Handling

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Use anhydrous solvents such as DMF or DMSO; avoid premature hydrolysis or deprotection.

This product integrates protecting group chemistry with carboxyl reactivity in a PEG1 scaffold, specifically offering compact and versatile conjugation capability.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.