Phthalimidoxy-PEG1-acid
This product is a heterobifunctional PEG linker containing a phthalimidoxy protecting group, a PEG1 spacer, and a terminal carboxylic acid. It specifically enables protecting group strategies, amide coupling, and conjugation, offering solubility and compact structure.
Key Features and Benefits
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Phthalimidoxy Group: Provides stability and controlled deprotection for orthogonal chemistry.
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Carboxylic Acid: Couples efficiently with amines to form stable amide bonds.
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PEG1 Spacer: Offers compact solubility and low steric hindrance.
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Versatile Reactivity: Combines protecting group chemistry with carboxyl functionality.
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High Purity: Ensures reproducibility in synthesis and conjugation workflows.
Applications
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Bioconjugation: Links biomolecules through amide bond formation.
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Protecting Group Strategies: Enables staged reactivity in synthetic workflows.
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Probe Development: Serves as an intermediate for multifunctional probe design.
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Medicinal Chemistry: Supports drug design and linker development.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid premature hydrolysis or deprotection.
This product integrates protecting group chemistry with carboxyl reactivity in a PEG1 scaffold, specifically offering compact and versatile conjugation capability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
