Thiazole Orange NHS Ester is a fluorescent dye that labels biomolecules like peptides, proteins, and amino-DNA by reacting with amines. Its fluorescence increases significantly when bound to double-stranded DNA, RNA, or other molecules, making it ideal for studying nucleic acids, proteins, and small analytes.
Key Features:
- Sensitive Fluorescence:
- Strong fluorescence when bound to DNA or RNA, increasing ~1,000-fold.
- Efficient Labeling:
- Reacts with primary amines for precise biomolecule tagging.
- Spectral Properties:
- Excitation: ~509 nm (with DNA).
- Emission: ~532 nm.
Applications:
- Nucleic Acid Studies:
- Labels DNA and RNA for hybridization and interaction studies.
- Protein and Peptide Labeling:
- Tags biomolecules for imaging and biochemical assays.
- Fluorescence Imaging:
- Visualizes molecular interactions in live cells and microscopy.
- Molecular Interaction Research:
- Studies nucleic acid-protein binding and detects small analytes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.