Tetrazine-PEG3-Alcohol is a versatile reagent designed for bioorthogonal conjugation and functionalization. It features a tetrazine group for rapid and selective IEDDA reactions with strained alkenes, such as TCO, and a hydroxyl group for downstream modifications. The PEG3 spacer improves aqueous solubility, reduces steric hindrance, and ensures compatibility in complex biological systems.
Features
- Tetrazine Group: Enables fast, selective, and bioorthogonal IEDDA reactions.
- Hydroxyl Group: Provides flexibility for further derivatization.
- PEG3 Spacer: Enhances solubility and minimizes steric interference.
- High Purity: ≥95% for reproducible and reliable results.
- Biocompatibility: Suitable for use in sensitive biological environments.
Applications
- Bioconjugation: Functionalization of biomolecules for labeling or modification.
- Imaging: Development of fluorescent or radiolabeled probes.
- Diagnostics: Functionalization for biosensors and assay development.
- Material Science: Synthesis of hydrogels and functional polymers.
- Drug Delivery: Preparation of drug conjugates and targeted delivery systems.
- Chemical Biology: Studies involving live cells and complex biological systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.