TCO-PEG3-triethoxysilane (CAS 2250217-32-2) is a crosslinking reagent combining a trans-cyclooctene (TCO) group with a triethoxysilane moiety. The triethoxysilane end allows surface modifications on glass and silica materials through covalent bonding, while the TCO group supports rapid, bioorthogonal click reactions with tetrazine-containing compounds.
Key Features:
- Surface Modification: Functionalizes glass and silica surfaces, improving hydrophilicity and biocompatibility.
- Bioorthogonal Reactivity: Enables fast, catalyst-free reactions with tetrazines through inverse-electron demand Diels-Alder cycloaddition.
- Versatile Applications: Suitable for materials science, nanotechnology, and chemical biology.
TCO-PEG3-triethoxysilane Applications:
- Surface Coating: Enhances biosensors, diagnostic tools, and microfluidic devices.
- Nanoparticle Stabilization: Improves stability and dispersion in biomedical uses.
- Bioconjugation: Facilitates precise labeling and conjugation of biomolecules.
Specifications:
- Purity: ≥95%
- Solubility: Soluble in DMSO, DCM, and DMF
- Storage: Store at -20°C
This reagent is widely used in research for applications requiring precise and efficient bioconjugation or surface modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
