TAMRA PEG4 Tetrazine: Advanced Reagent for Bioorthogonal Chemistry
Overview
TAMRA PEG4 Tetrazine is a cutting-edge reagent designed for bioorthogonal chemistry applications. Combining TAMRA fluorescence with PEG4 linkers and tetrazine chemistry, it offers superior performance in labeling, imaging, and tracking biological molecules. This versatile compound is ideal for researchers in fields such as cell biology, molecular imaging, and drug development.
Key Features
- Fluorescent Labeling: TAMRA (Tetramethylrhodamine) provides bright and stable fluorescence, making it ideal for sensitive detection and imaging.
- PEG4 Linker: The PEG4 (Polyethylene Glycol) spacer enhances solubility and reduces non-specific binding, ensuring cleaner results in complex biological systems.
- Tetrazine Chemistry: Tetrazine provides a fast, selective, and bioorthogonal reaction with trans-cyclooctene (TCO) and other dienophile-containing compounds, facilitating precise biomolecule labeling.
Applications
1. Bioorthogonal Labeling
- Objective: Tag biomolecules for visualization and tracking.
- Benefits: Enables precise labeling with minimal background interference.
- Usage: Ideal for tracking proteins, nucleic acids, and small molecules in live cells and tissues.
2. Molecular Imaging
- Objective: Visualize and monitor biological processes in real time.
- Benefits: TAMRA’s fluorescence allows for high-resolution imaging of cellular and subcellular structures.
- Usage: Suitable for fluorescence microscopy, flow cytometry, and live-cell imaging.
3. Drug Development
- Objective: Investigate drug-target interactions and validate compound efficacy.
- Benefits: Provides accurate data on drug distribution and binding.
- Usage: Useful in screening assays and pharmacokinetic studies.
Benefits
- High Sensitivity: Bright TAMRA fluorescence ensures detectable signals even in low-abundance samples.
- Enhanced Specificity: PEG4 spacer minimizes non-specific interactions, improving assay specificity.
- Fast Reaction: Tetrazine chemistry enables rapid and efficient labeling reactions.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
