t-Boc-N-Amido-PEG7-amine
This product is a bifunctional PEG7 linker with a Boc-protected amide and a terminal primary amine. The PEG7 spacer enhances solubility and flexibility, while the Boc group provides acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Stable carbamate protection, removable under acidic conditions.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and electrophiles.
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PEG7 Spacer: Provides hydrophilicity, moderate chain length, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
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Orthogonal Design: Supports selective and stepwise synthetic strategies.
Applications:
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Bioconjugation: Attach proteins, peptides, or small molecules with PEG spacing.
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Drug Delivery: PEGylated linker to enhance solubility and pharmacokinetics.
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Surface Modification: Functionalize nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Useful intermediate in orthogonal, PEG-based scaffold design.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and amine stability.
This product combines a Boc-protected amide with a reactive amine handle, making it an especially versatile PEG7 linker for orthogonal synthesis, bioconjugation, and drug delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
