t-Boc-N-Amido-PEG6-alcohol
This product is a PEG6 linker with a Boc-protected amide and a terminal hydroxyl group. The PEG6 spacer provides hydrophilicity, flexibility, and medium-length spacing, while the Boc group offers acid-labile protection for controlled and orthogonal conjugation workflows.
Key Features and Benefits:
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Boc-Protected Amide: Acid-labile protecting group for selective, stepwise synthesis.
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Hydroxyl Group: Serves as a versatile handle for activation or derivatization.
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PEG6 Spacer: Provides solubility, flexibility, and reduced steric hindrance.
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High Purity: Ensures reliable performance in sensitive bioconjugation workflows.
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Orthogonal Reactivity: Supports multifunctional and controlled conjugation strategies.
Applications:
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Bioconjugation: Enables precise protein, peptide, and biomolecule modification.
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Drug Delivery: PEGylated linker enhances solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
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Synthetic Chemistry: Acts as an intermediate in PEGylated scaffold design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and hydroxyl stability.
This product provides dual reactivity and medium PEG spacing, making it an excellent choice specifically for orthogonal synthesis, bioconjugation, and advanced material modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
