t-Boc-N-Amido-PEG4-alcohol
This product is a short PEG4 linker with a Boc-protected amide and a terminal hydroxyl group. The PEG4 spacer provides moderate hydrophilicity and flexibility, while the Boc group offers acid-labile protection for orthogonal and controlled conjugation workflows.
Key Features and Benefits:
-
Boc-Protected Amide: Acid-labile protection for selective, stepwise synthesis.
-
Hydroxyl Group: Provides a versatile handle for derivatization or activation.
-
PEG4 Spacer: Balances solubility with compact chain length and reduced steric hindrance.
-
High Purity: Ensures reproducibility in sensitive workflows.
-
Orthogonal Reactivity: Supports multifunctional and controlled synthetic strategies.
Applications:
-
Bioconjugation: Enables precise protein, peptide, and biomolecule modification.
-
Drug Delivery: PEGylated linker improves solubility, stability, and pharmacokinetics.
-
Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
-
Synthetic Chemistry: Serves as a useful intermediate in orthogonal scaffold construction.
Storage and Handling:
-
Storage: Store at –20 °C in a dry, light-protected container.
-
Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and hydroxyl integrity.
This product offers controlled reactivity with moderate PEG spacing, making it an especially valuable tool for orthogonal conjugation, bioconjugation, and advanced synthetic workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
