t-Boc-N-Amido-PEG36-acid
This product is a long-chain PEG36 linker with a Boc-protected amide and a terminal carboxylic acid. The PEG36 spacer provides exceptional hydrophilicity, extended flexibility, and long-range spacing, while the Boc group offers acid-labile protection for selective, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Acid-labile protecting group for controlled, stepwise synthesis.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG36 Spacer: Provides very long hydrophilic spacing with reduced steric hindrance.
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High Purity: Ensures reliable performance in bioconjugation and material science.
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Orthogonal Reactivity: Supports multifunctional and advanced conjugation schemes.
Applications:
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Bioconjugation: Facilitates precise biomolecule attachment with long PEG spacing.
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Drug Delivery: PEGylated linker improves solubility, pharmacokinetics, and stability.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
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Material Science: Ideal for PEGylated scaffolds and biomaterial design.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and acid stability.
This product provides extended PEG spacing with dual functionality, making it an especially versatile reagent for orthogonal synthesis, bioconjugation, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
