t-Boc-N-Amido-PEG3-CH2COOH
This product is a short PEG3 linker with a Boc-protected amide and a terminal carboxymethyl group. The PEG3 spacer provides hydrophilicity and flexibility, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Acid-labile protection for selective deprotection.
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Carboxymethyl Group: Couples efficiently with amines to form stable amide bonds.
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PEG3 Spacer: Provides compact solubility and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Orthogonal Design: Supports controlled and stepwise synthetic strategies.
Applications:
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Bioconjugation: Enables precise attachment of proteins, peptides, and biomolecules.
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Drug Delivery: Improves solubility and pharmacokinetics of therapeutic payloads.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Useful intermediate for PEGylated scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and acid reactivity.
This product offers short PEG spacing with dual reactivity, making it an especially versatile tool for orthogonal synthesis, bioconjugation, and material science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
