t-Boc-N-Amido-PEG3-Azide is a versatile polyethylene glycol (PEG) linker that features a tert-butoxycarbonyl (t-Boc) protected amine and an azide group, connected by a PEG3 spacer. As a result, it is ideal for bioconjugation, drug delivery, and surface modification. Additionally, it enhances solubility, reduces steric hindrance, and supports efficient click chemistry reactions.
Key Features:
- Bifunctional linker with both a t-Boc-protected amine and an azide group
- PEG3 spacer improves flexibility and solubility
- Fully compatible with click chemistry (CuAAC)
- Acid-labile t-Boc group allows easy removal
- Furthermore, it minimizes steric hindrance in reactions
Applications:
- Bioconjugation of proteins, peptides, and other biomolecules
- Development of advanced drug delivery systems
- Surface functionalization for materials science applications
- Synthesis of bio-orthogonal probes for research
- Polymer modification and crosslinking for material enhancement
CAS Number: 642091-68-7
Molecular Formula: C12H26N4O5
Molecular Weight: 322.36 g/mol
Conclusion:
In summary, t-Boc-N-Amido-PEG3-Azide (CAS 642091-68-7) is a highly effective linker for chemical conjugation and functionalization. It combines a protected amine, a reactive azide group, and a flexible PEG3 spacer. Therefore, it is an essential tool for researchers in biotechnology, pharmaceuticals, and materials science. Moreover, it offers reliable performance for applications such as bioconjugation, drug delivery, and surface modification.
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