t-Boc-N-Amido-PEG3-alcohol
This product is a short PEG3 linker with a Boc-protected amide and a terminal hydroxyl group. The PEG3 spacer provides moderate hydrophilicity and flexibility, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation workflows.
Key Features and Benefits:
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Boc-Protected Amide: Acid-labile protection for selective, stepwise synthesis.
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Hydroxyl Group: Provides a versatile handle for derivatization or activation.
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PEG3 Spacer: Short hydrophilic chain with reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Orthogonal Reactivity: Combines protection and hydroxyl reactivity for multifunctional design.
Applications:
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Bioconjugation: Compact linker for protein, peptide, and biomolecule modification.
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Drug Delivery: PEGylated linker improves solubility and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Useful intermediate for orthogonal stepwise synthesis.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and hydroxyl integrity.
This product offers compact PEG spacing with dual functionality, making it an especially versatile tool for orthogonal conjugation, controlled synthesis, and drug delivery applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
