t-Boc-N-Amido-PEG24-alcohol
This product is a high-purity PEG reagent with a t-Boc–protected amide and a terminal hydroxyl linked by a long PEG24 spacer. The t-Boc group offers acid-labile, orthogonal protection, while PEG24 boosts solubility, reduces steric hindrance, and provides flexible spacing—ideal for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Protected Amide Functionality: t-Boc group ensures controlled, selective deprotection.
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Long PEG24 Spacer: Improves solubility, flexibility, and accessibility of functional groups.
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High Purity: Reliable performance in sensitive and reproducible workflows.
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Orthogonal Reactivity: Supports stepwise synthesis in complex conjugation schemes.
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Versatile Use: Suitable for both aqueous and organic reactions.
Applications:
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Bioconjugation: Attach biomolecules with precise spatial control.
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Drug Delivery: Incorporate PEG spacers to enhance pharmacokinetics.
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Surface Modification: Introduce functional handles to polymers, nanoparticles, or biomaterials.
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Material Science: Build advanced PEGylated materials with tailored properties.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF) to maintain t-Boc and hydroxyl integrity.
This product delivers extended PEG spacing with orthogonal protection, making it an especially versatile tool for advanced synthetic and bioconjugation applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
