t-Boc-N-Amido-PEG23-Azide (BocNH-PEG23-N₃)
This compound is a polyethylene glycol (PEG) derivative featuring a Boc-protected amine and an azide group, separated by a 23-unit PEG spacer. The azide group facilitates bioorthogonal conjugation via click chemistry, while the Boc group can be removed under mild acidic conditions to reveal a free amine for further functionalization. The extended PEG spacer enhances solubility and flexibility, making it valuable in bioconjugation, drug delivery, and materials science applications.
Chemical Properties:
- Molecular Formula: C₅₃H₁₀₆N₄O₂₅
- Molecular Weight: 1199.37 g/mol
- Purity: ≥95%
Applications:
- Bioconjugation: Enables the attachment of biomolecules through click chemistry reactions, forming stable triazole linkages.
- Drug Delivery: Serves as a linker in the development of targeted therapeutics, improving solubility and pharmacokinetics.
- Materials Science: Utilized in surface modification to enhance biocompatibility and reduce nonspecific binding.
Storage and Handling:
- Storage Conditions: Store at -20°C in a dry environment to maintain stability.
- Safety Measures: Handle with appropriate protective equipment; consult the Safety Data Sheet (SDS) for detailed information.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
