t-Boc-N-Amido-PEG23-amine
This product is a high-purity PEG linker featuring a Boc-protected amine and a free terminal amine, connected by a PEG23 spacer. This design specifically provides solubility, flexibility, and selective deprotection for versatile bioconjugation and drug delivery applications.
Key Features and Benefits
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Boc-Protected Amine – Enables selective deprotection under mild acidic conditions for controlled functionalization.
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Free Terminal Amine – Reacts with activated esters, carboxyl groups, or other electrophiles for conjugation.
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PEG23 Spacer – Provides excellent water solubility, reduced steric hindrance, and extended reach in conjugates.
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High Purity – Suitable for pharmaceutical, diagnostic, and biomaterials research.
Applications
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Spacer/linker for drug delivery systems and PEGylated therapeutics
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Bioconjugation of proteins, peptides, and small molecules
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Surface modification and functionalization in nanotechnology
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Scaffold for dual-functional linker strategies requiring orthogonal amine protection
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DCM, DMF). Avoid repeated freeze–thaw cycles.
This product is a PEG linker with one Boc-protected and one free amine, connected by a PEG23 spacer. It provides excellent solubility, flexibility, and selective reactivity, making it especially ideal for bioconjugation and drug delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
