t-Boc-N-Amido-PEG2-CH2COOH
This product is a bifunctional PEG2 linker with a Boc-protected amide and a terminal carboxymethyl group. The PEG2 spacer improves solubility and flexibility, while the Boc group provides acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Stable, acid-labile protection for stepwise synthesis.
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Carboxymethyl Group: Couples with amines to form stable amide bonds.
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PEG2 Spacer: Compact chain providing solubility with minimal steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Orthogonal Design: Supports selective and controlled conjugation strategies.
Applications:
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Bioconjugation: Enables precise attachment of biomolecules with short PEG spacing.
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Drug Delivery: Enhances solubility and stability of therapeutic payloads.
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Surface Modification: Functionalizes nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Serves as a protected intermediate in PEG-based scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and acid reactivity.
This product provides a compact PEG spacer with Boc-protected and carboxymethyl functionalities, making it an especially versatile reagent for orthogonal synthesis and advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
