t-Boc-N-Amido-PEG2-amine
This product is a short PEG2 linker with a Boc-protected amide and a terminal primary amine. The PEG2 spacer provides hydrophilicity and compact flexibility, while the Boc group offers acid-labile protection for selective, orthogonal conjugation strategies.
Key Features and Benefits:
-
Boc-Protected Amide: Acid-labile protecting group for controlled, stepwise synthesis.
-
Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
-
PEG2 Spacer: Provides compact hydrophilic spacing with minimal steric hindrance.
-
High Purity: Ensures reproducibility in bioconjugation and synthetic workflows.
-
Orthogonal Reactivity: Enables selective and multifunctional conjugation strategies.
Applications:
-
Bioconjugation: Compact linker for protein, peptide, and biomolecule modification.
-
Drug Delivery: PEGylated linker enhances solubility and pharmacokinetics.
-
Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
-
Synthetic Chemistry: Useful as a protected intermediate in PEGylated scaffold design.
Storage and Handling:
-
Storage: Store at –20 °C, protected from light and moisture.
-
Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and amine stability.
This product provides compact PEG spacing with dual functionality, making it an especially versatile tool for orthogonal synthesis, bioconjugation, and advanced material science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
