t-Boc-N-Amido-PEG2-alcohol
This product is a bifunctional PEG2 linker with a Boc-protected amide and a terminal hydroxyl group. The short PEG2 spacer provides hydrophilicity and flexibility, while the Boc group offers acid-labile protection for orthogonal synthesis strategies.
Key Features and Benefits:
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Boc-Protected Amide: Stable, acid-labile protection for controlled deprotection.
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Hydroxyl Group: Provides a handle for further derivatization or functionalization.
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PEG2 Spacer: Enhances solubility while minimizing steric hindrance.
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High Purity: Ensures reproducibility in bioconjugation and synthesis workflows.
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Orthogonal Reactivity: Supports stepwise and selective conjugation schemes.
Applications:
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Bioconjugation: Attach biomolecules with controlled PEG spacing.
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Drug Delivery: Spacer-linker for improved solubility and pharmacokinetics.
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Surface Modification: Functionalize nanoparticles, hydrogels, or polymers.
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Synthetic Chemistry: Useful intermediate for PEG-based scaffolds and materials.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF) to preserve hydroxyl and Boc stability.
This product provides a short PEG spacer with Boc-protected and hydroxyl functionalities, making it an especially efficient linker for orthogonal conjugation and synthetic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
