t-Boc-N-Amido-PEG2-acid
This product is a short PEG2 linker with a Boc-protected amide and a terminal carboxylic acid. The PEG2 spacer provides hydrophilicity and compact flexibility, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Provides acid-labile protection for selective, stepwise synthesis.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG2 Spacer: Offers compact solubility and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
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Orthogonal Reactivity: Enables multifunctional and controlled conjugation strategies.
Applications:
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Bioconjugation: Compact linker for proteins, peptides, and biomolecules.
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Drug Delivery: Improves solubility and pharmacokinetics in therapeutic systems.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, or polymers.
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Synthetic Chemistry: Serves as a protected intermediate for orthogonal synthesis.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and acid stability.
This product provides compact PEG spacing with dual reactivity, making it an especially versatile tool for orthogonal conjugation, drug delivery, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
