t-Boc-N-Amido-PEG10-amine
This product is a high-purity, heterobifunctional PEG linker with a tert-butoxycarbonyl (t-Boc)–protected amide at one end and a primary amine at the other, separated by a PEG10 spacer. The t-Boc group allows controlled deprotection under mild acidic conditions, while the free amine enables coupling with activated esters, isocyanates, or other electrophiles. The PEG10 spacer specifically enhances solubility, flexibility, and reduces steric hindrance for efficient conjugation in aqueous and organic systems.
Key Features
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Bifunctional design with t-Boc-protected amide and primary amine
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Orthogonal protection for stepwise conjugation strategies
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PEG10 spacer improves hydrophilicity, solubility, and flexibility
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High chemical purity and stability
Applications
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Stepwise bioconjugation and multi-functional labeling
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Protein, peptide, and antibody modification
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Nanoparticle and surface functionalization
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Drug delivery and biomaterial engineering
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Bring to room temperature before opening
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Avoid repeated freeze–thaw cycles
This product combines a t-Boc-protected amide with a reactive amine, linked by a PEG10 spacer for solubility and reduced steric hindrance, especially ideal for controlled, orthogonal conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
