t-Boc-N-Amido-PEG1-alcohol
This product is a short-chain PEG1 linker with a Boc-protected amide and a terminal hydroxyl group. The compact PEG1 spacer provides limited hydrophilicity and spacing, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Stable, acid-labile protection for selective deprotection.
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Hydroxyl Group: Versatile handle for derivatization or activation.
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PEG1 Spacer: Provides compact hydrophilicity with minimal steric hindrance.
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High Purity: Ensures reliable performance in conjugation workflows.
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Orthogonal Reactivity: Supports stepwise and controlled synthesis strategies.
Applications:
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Bioconjugation: Enables compact PEG spacing for protein and peptide modification.
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Drug Delivery: Improves solubility and stability in PEGylated conjugates.
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Surface Modification: Functionalizes nanoparticles and polymers with minimal spacing.
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Synthetic Chemistry: Serves as a protected intermediate in orthogonal synthesis.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and hydroxyl integrity.
This product provides compact PEG spacing with dual reactive groups, making it an especially versatile tool for controlled conjugation and synthetic workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
