Sulfo-Cyanine3 DBCO is a water-soluble fluorescent dye featuring a dibenzocyclooctyne (DBCO) group, facilitating copper-free click chemistry reactions with azides. This property enables efficient and biocompatible labeling of biomolecules.
Key Features:
- Water Solubility: The sulfonated structure ensures high solubility in aqueous environments, eliminating the need for organic solvents during labeling procedures.
- DBCO Functional Group: The DBCO moiety reacts rapidly and selectively with azide groups via strain-promoted alkyne-azide cycloaddition (SPAAC), allowing for copper-free click chemistry.
- Bright Fluorescence: Sulfo-Cyanine3 exhibits strong fluorescence with an excitation maximum around 548–555 nm and an emission maximum near 563–570 nm, providing high-contrast imaging capabilities.
Applications:
- Bioconjugation: Facilitates the copper-free labeling of azide-modified biomolecules, such as proteins, nucleic acids, and glycans, under mild conditions.
- Fluorescence Imaging: Enables visualization of labeled biomolecules in live-cell imaging, flow cytometry, and other fluorescence-based techniques.
- Diagnostics and Therapeutics: Assists in the development of diagnostic assays and targeted therapeutic delivery systems through specific biomolecule labeling.
Sulfo-Cyanine3 DBCO is a versatile tool for researchers requiring efficient and bright labeling of azide-containing biomolecules in various biological studies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
