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SPDP-PEG11-SPDP

Catalog #: AP13821
Name: SPDP-PEG11-SPDP
Chemical Formula: C40H66N4O13S4
Molecular Weight: 939.2
CAS: nan
Purity: ≥98%
Availability: In Stock

SPDP-PEG11-SPDP

$480.00 – $1,530.00

SPDP-PEG11-SPDP is a PEGylated bifunctional reagent featuring a PEG11 chain and two SPDP groups. The SPDP groups are reactive to both amines and thiols, facilitating the formation of stable disulfide bonds and enabling intracellular crosslinking due to their membrane permeability. The PEG11 spacer enhances solubility and flexibility, making this compound ideal for creating stable conjugates and controlled release systems in therapeutic and diagnostic applications.

UnitPriceQuantity
250 mg$480
500 mg$850
1 g$1530

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SKU: AP13821 Category:
Description

SPDP-PEG11-SPDP

SPDP-PEG11-SPDP is a versatile reagent used in biochemical and pharmaceutical research. It combines a PEG11 (polyethylene glycol) spacer with two SPDP (N-Succinimidyl 3-(2-pyridyldithio)propionate) groups, enhancing its use in creating stable conjugates and targeted drug delivery systems.

Key Features

  • PEG11 Chain: Improves solubility and flexibility in aqueous solutions.
  • SPDP Groups: React with amines and thiols to form stable disulfide bonds.
  • Membrane Permeable: Facilitates intracellular crosslinking.
  • Enhanced Stability: PEG11 spacer boosts the stability and solubility of conjugates.

Applications

  • Bioconjugation: Links biomolecules like proteins and peptides with improved stability.
  • Drug Delivery: Develops targeted drug delivery systems with controlled release.
  • Controlled Release: Enables the release of therapeutic agents through disulfide bond cleavage.

Advantages

  • Enhanced Solubility: PEG11 chain increases solubility in aqueous environments.
  • Stable Conjugation: Reliable formation of stable conjugates with SPDP groups.
  • Intracellular Capability: Membrane permeability allows for effective intracellular crosslinking.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.

Shipping & Delivery
Ships within: 24 hours
Storage condition: -20 ° C
Shipping: Ambient Temperature