PTAD-PEG4-Alkyne: Overview and Applications
Product Summary
PTAD-PEG4-Alkyne is a bioconjugation linker with a PTAD group for selective tyrosine labeling and an alkyne for click chemistry. The PEG4 spacer enhances solubility and flexibility, making it ideal for stable, targeted attachment to tyrosine residues in proteins, peptides, and small molecules. This linker works well in complex biological systems, providing reliable labeling and functionalization.
Key Benefits
- Selective Tyrosine Targeting: Specifically labels tyrosine, avoiding interactions with other amino acids.
- Enhanced Solubility: The PEG4 spacer increases solubility and flexibility in aqueous solutions.
- Click Chemistry Compatibility: The alkyne group supports CuAAC reactions for efficient, bioorthogonal conjugation.
- Stable Linkage: Creates a durable and stable connection in diverse biological conditions.
Applications
- Bioconjugation and Labeling
- Enables selective, stable labeling of tyrosine residues for tracking proteins and peptides.
- Click Chemistry
- The alkyne group allows CuAAC click chemistry with azides, offering flexible bioconjugation options.
- Drug Delivery and Targeting
- Supports precise attachment of therapeutic agents for targeted delivery.
- Surface Functionalization
- Ideal for attaching bioactive molecules to surfaces, enhancing biosensors and diagnostic tools.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
