Propargyl-PEG6-alcohol
This product is a bifunctional PEG6 linker with a terminal alkyne for click chemistry and a hydroxyl group for derivatization. The PEG6 spacer specifically provides solubility, flexibility, and moderate spacing, making it highly suitable for bioconjugation, drug delivery, and advanced material design.
Key Features and Benefits:
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Propargyl Group: Enables CuAAC or SPAAC click chemistry with azides.
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Hydroxyl Group: Provides a functional handle for further modification or activation.
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PEG6 Spacer: Offers hydrophilicity and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Functionality: Supports orthogonal and multistep synthetic strategies.
Applications:
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Click Chemistry: Azide–alkyne ligation for orthogonal labeling and conjugation.
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Bioconjugation: Link proteins, peptides, or small molecules with PEG spacing.
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Drug Delivery: PEGylated linker improves solubility and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve alkyne and hydroxyl stability.
This product provides alkyne and hydroxyl groups with moderate PEG spacing, making it an especially versatile reagent for click chemistry, bioconjugation, and material science applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
