Propargyl-PEG4-alcohol
This product is a bifunctional PEG4 linker with a terminal alkyne for click chemistry and a hydroxyl group for further derivatization. The PEG4 spacer enhances solubility and flexibility, making it an especially versatile building block for bioconjugation, drug delivery, and material science applications.
Key Features and Benefits:
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Propargyl Group: Enables CuAAC or SPAAC click chemistry with azides.
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Hydroxyl Group: Provides a versatile handle for derivatization or activation.
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PEG4 Spacer: Improves solubility, reduces steric hindrance, and enhances flexibility.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Functionality: Supports orthogonal conjugation and multistep synthesis.
Applications:
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Click Chemistry: Alkyne–azide bioorthogonal labeling for biomolecules and polymers.
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Bioconjugation: Functionalize proteins, peptides, or nanoparticles.
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Drug Delivery: PEGylated linker improves solubility and pharmacokinetics of payloads.
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Material Modification: Useful for polymer scaffolds, hydrogels, and nanomaterials.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain alkyne and hydroxyl stability.
This product provides a compact PEG spacer with click-ready alkyne and hydroxyl functionalities, making it an especially powerful tool for controlled conjugation and advanced material design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
