Propargyl-PEG3-alcohol
This product is a compact PEG3 linker with a terminal alkyne for click chemistry and a hydroxyl group for derivatization. The PEG3 spacer provides hydrophilicity, flexibility, and short spacing, making it especially suitable for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Propargyl Group: Enables CuAAC and SPAAC click chemistry with azides.
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Hydroxyl Group: Serves as a versatile handle for activation or modification.
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PEG3 Spacer: Provides compact solubility and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Combines click-ready alkyne chemistry with hydroxyl versatility.
Applications:
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Click Chemistry: Bioorthogonal azide–alkyne ligation for labeling and conjugation.
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Bioconjugation: Facilitates protein, peptide, and small-molecule modification.
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Drug Delivery: PEGylated linker enhances solubility, pharmacokinetics, and stability.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve alkyne and hydroxyl stability.
This product offers compact PEG spacing with alkyne and hydroxyl groups, making it an especially versatile building block for conjugation, drug delivery, and material science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.