Propargyl-PEG2-alcohol
This product is a compact PEG2 linker with a terminal alkyne for click chemistry and a hydroxyl group for derivatization. The PEG2 spacer provides hydrophilicity and short, flexible spacing, making it especially useful for bioconjugation, drug delivery, and material science applications.
Key Features and Benefits:
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Propargyl Group: Supports CuAAC or SPAAC click chemistry with azides.
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Hydroxyl Group: Serves as a versatile handle for further activation or modification.
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PEG2 Spacer: Provides hydrophilicity and reduced steric hindrance in compact form.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Reactivity: Combines alkyne click functionality with hydroxyl versatility.
Applications:
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Click Chemistry: Azide–alkyne ligation for bioorthogonal conjugation.
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Bioconjugation: Enables efficient attachment of biomolecules with PEG spacing.
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Drug Delivery: PEGylated linker improves solubility and stability of conjugates.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve alkyne and hydroxyl reactivity.
This product provides dual reactivity in a compact PEG spacer, making it an especially versatile reagent for click chemistry, conjugation, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.