The aldehyde group readily reacts with primary amines, aminooxy and hydrazide. After a hydrazine deprotection, the free oxyamine group that can react with an aldehyde to form a reversible oxime bond. If reduced, the oxime can be converted to a stable carbon-N bond. The PEG spacer increase the solubility of the resulting complex in aqueous media.
Phthalamidoxy-PEG2-CH2-ald is a chemical compound used in bioconjugation and biochemistry research. It is a derivative of polyethylene glycol (PEG) and is used to link different molecules together, forming a bridge between them. This is a common method used in drug delivery and other types of research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.