PEI-B-PEG, n 10K, m 5K is a branched polyethyleneimine (PEI)-polyethylene glycol (PEG) copolymer and specifically combines an amine-rich branched PEI framework with hydrophilic PEG segments for biomolecular complexation, polymer functionalization, and biomaterial research.
Key Features and Benefits
- Branched PEI Structure: Features a branched polyethyleneimine framework with a high density of accessible amine groups.
- PEI MW 10K: Provides an amine-rich branched PEI component with multiple protonatable amines for electrostatic interactions and functionalization.
- PEG MW 5K: Provides hydrophilic polyethylene glycol segments that specifically contribute substantial hydrophilic character to the polymer.
- Cationic Character: Branched PEI provides positive charge under suitable pH conditions for interactions with negatively charged molecules and materials.
- Amine-Rich Structure: Primary, secondary, and tertiary amines contribute to PEI’s cationic properties and chemical versatility.
- PEI-Rich Composition: The 10K PEI and 5K PEG components specifically provide a PEI-rich architecture with a substantial hydrophilic PEG contribution.
- Hydrophilic PEG Segment: PEG contributes hydrophilicity and specifically helps balance the cationic properties of the branched PEI component.
- Functionalization Platform: Available PEI amine groups specifically provide sites for conjugation with compatible amine-reactive molecules.
Applications
- Biomolecular Complexation: Cationic PEI supports electrostatic interactions with compatible negatively charged biomolecules and materials.
- Nucleic Acid Complexation: Supports research involving electrostatic complexation with compatible DNA, RNA, and other polyanionic molecules.
- Polymer Functionalization: Available PEI amine groups specifically provide sites for introducing additional functionality.
- Nanoparticle Formulation: Supports development of cationic polymeric nanoparticles and related nanoscale systems.
- Polymer Complexation: Supports formation and study of complexes with compatible anionic polymers and materials.
- Drug Delivery: Supports development of functional cationic polymer systems for delivery research.
- Surface Modification: Amine-rich PEI supports development of functional coatings and modified surfaces.
- Biomaterial Research: Supports development of cationic polymers, complexes, nanoparticles, coatings, and related biomaterials.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
PEI-B-PEG, n 10K, m 5K combines an amine-rich branched PEI framework with hydrophilic PEG segments and specifically supports biomolecular complexation, polymer functionalization, nanoparticle formulation, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
