PEI-B-PEG, n 2K, m 2K is a branched polyethyleneimine (PEI)-polyethylene glycol (PEG) copolymer and specifically combines a compact, amine-rich branched PEI framework with hydrophilic PEG segments for biomolecular complexation, polymer functionalization, and biomaterial research.
Key Features and Benefits
- Branched PEI Structure: Features a compact branched polyethyleneimine framework with multiple accessible amine groups.
- PEI MW 2K: Provides a low molecular weight branched PEI component with multiple protonatable amines.
- PEG MW 2K: Provides compact hydrophilic polyethylene glycol segments that help tune the polymer’s physicochemical properties.
- Cationic Character: Branched PEI provides positive charge under suitable pH conditions for interactions with negatively charged molecules and materials.
- Amine-Rich Structure: Primary, secondary, and tertiary amines specifically contribute to PEI’s cationic properties and chemical versatility.
- Balanced Composition: The 2K PEI and 2K PEG components specifically provide a balanced molecular weight combination of cationic PEI and hydrophilic PEG.
- Hydrophilic PEG Segment: PEG contributes hydrophilicity while branched PEI provides cationic and amine functionality.
- Functionalization Platform: Available PEI amine groups specifically provide sites for conjugation with compatible amine-reactive molecules.
Applications
- Biomolecular Complexation: Cationic PEI supports electrostatic interactions with compatible negatively charged biomolecules and materials.
- Nucleic Acid Complexation: Supports research involving electrostatic complexation with compatible DNA, RNA, and other polyanionic molecules.
- Polymer Functionalization: Available PEI amine groups specifically provide sites for introducing additional functionality.
- Nanoparticle Formulation: Supports development of functional polymeric nanoparticles and related nanoscale systems.
- Polymer Complexation: Supports formation and study of complexes with compatible anionic polymers and materials.
- Drug Delivery: Supports development of functional cationic polymer systems for delivery research.
- Surface Modification: Amine-rich PEI supports development of functional coatings and modified surfaces.
- Biomaterial Research: Supports development of functional polymers, complexes, nanoparticles, coatings, and related biomaterials.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
PEI-B-PEG, n 2K, m 2K combines a compact, amine-rich branched PEI framework with compact hydrophilic PEG segments and specifically supports biomolecular complexation, polymer functionalization, nanoparticle formulation, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
