OH-PEG8-OH (Octaethylene Glycol) (CAS: 5117-19-1)
OH-PEG8-OH (Octaethylene Glycol), is a linear polyethylene glycol with eight ethylene glycol units and hydroxyl (-OH) groups at both ends. Moreover, its excellent solubility, biocompatibility, and hydrophilic nature make it a reliable choice for a wide range of applications, from chemical synthesis to biotechnology and pharmaceuticals.
Key Features
- Molecular Formula: C₁₆H₃₄O₉
- Molecular Weight: 370.43 g/mol
- Structure: HO-(CH₂CH₂O)₈-H
- Physical Form: Clear, viscous liquid or low-melting solid
- Solubility: Dissolves easily in water and organic solvents
Applications
1. Chemical Synthesis
OH-PEG8-OH provides dual hydroxyl groups, enabling it to function significantly as a reliable building block or intermediate for synthesizing larger polymers, surfactants, or PEGylated derivatives. Furthermore, versatility ensures compatibility with various synthetic processes.
2. Pharmaceuticals
In the pharmaceutical industry, OH-PEG8-OH (Octaethylene Glycol), enhances the solubility, stability, and bioavailability of active pharmaceutical ingredients (APIs). This property makes it an essential component in drug formulation and delivery systems.
3. Biotechnology
OH-PEG8-OH plays a key role in PEGylation, where it improves the solubility and stability of proteins, enzymes, and other biomolecules. Its dual hydroxyl groups also make it useful for bioconjugation and surface modifications.
4. Cosmetics
In cosmetics, OH-PEG8-OH serves as a humectant, emollient, and solubilizer. It boosts hydration, improves texture, and ensures the stability of skincare and haircare formulations.
Handling and Storage
Store OH-PEG8-OH in a tightly sealed container at room temperature to prevent moisture and light exposure. Use it promptly after opening to ensure maximum effectiveness. Always verify its compatibility with other reagents before use in formulations or reactions.
Overall, OH-PEG8-OH (Octaethylene Glycol) is a highly versatile compound. Its dual hydroxyl functionality, excellent solubility, and biocompatibility make it indispensable for applications in chemical synthesis, pharmaceuticals, biotechnology, and cosmetics. Whether for building polymers or enhancing formulations, it consistently delivers significantly reliable results.
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