Heptaethylene Glycol (HO-PEG7-OH) (CAS: 5617-32-3)
Heptaethylene Glycol (HO-PEG7-OH) is a linear polyethylene glycol with seven ethylene glycol units and terminal hydroxyl groups. Its excellent solubility in water and organic solvents makes it a versatile compound for use in chemical synthesis, pharmaceuticals, and biotechnology. Moreover, its unique properties enable diverse applications in several advanced fields.
Key Features:
Chemical Structure:
- Molecular Formula: C₁₄H₃₀O₈
- Molecular Weight: 326.38 g/mol
- Structure: HO-(CH₂CH₂O)₇-H
Physical Properties:
- Boiling Point: 244°C at 0.6 mmHg
- Density: 1.13 g/cm³
- Refractive Index: 1.4653 at 20°C
- Form: Clear, oily liquid
Applications:
Chemical Synthesis:
In chemical synthesis, Heptaethylene Glycol is used as a building block or intermediate in the creation of larger PEG molecules and derivatives. Additionally, its reactivity and solubility make it a preferred choice for various polymerization reactions.
Pharmaceuticals:
Within the pharmaceutical industry, it acts as a linker in drug development, significantly aiding in solubility enhancement and targeted delivery. Furthermore, its compatibility with various active pharmaceutical ingredients (APIs) ensures optimal performance in formulation design.
Biotechnology:
In biotechnology, it facilitates PEGylation to improve the stability and solubility of biomolecules. Besides this, it serves as an essential tool in bioconjugation processes, supporting advancements in therapeutics and diagnostics.
Handling and Storage:
To maintain product integrity, store Heptaethylene Glycol in a sealed container at room temperature. Additionally, keep it away from light and moisture to ensure long-term stability.
Overall, Heptaethylene Glycol’s dual hydroxyl functionality and excellent solubility make it a critical component for applications in polymer synthesis, drug delivery systems, and advanced bioconjugation techniques. In conclusion, its adaptability and multifunctionality continue to make it indispensable across a wide range of industries.
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