N,N-Bis(PEG2-propargyl)-N-4-oxo-butanoic acid
This product is a multifunctional PEG linker featuring dual propargyl (alkyne) groups for click chemistry and a terminal carboxylic acid for amide coupling. The PEG2 spacers provide solubility and compact flexibility, making it especially useful for probe design, drug delivery, and multifunctional bioconjugation.
Key Features and Benefits:
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Dual Propargyl Groups: Support CuAAC or SPAAC click chemistry with azides.
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Carboxylic Acid: Couples with amines to form stable amide bonds.
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PEG2 Spacers: Enhance solubility while maintaining compact steric accessibility.
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Multifunctional Design: Combines two click handles with amide chemistry.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Couples biomolecules through azide–alkyne click chemistry and amide linkage.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEGylated scaffolds with reactive handles.
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Synthetic Chemistry: Serves as a versatile building block for modular linkers.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature hydrolysis.
This prdouct integrates dual click-reactive alkynes with carboxyl chemistry in PEG2 scaffolds, specifically providing compact and versatile tools for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
