N,N-Bis(PEG2-azide)-N-PEG2-thiol
This product is a multifunctional PEG-based linker with two terminal azides for click chemistry and a free thiol for thiol-specific conjugation. The PEG2 spacers enhance solubility and flexibility, making it especially useful in multifunctional bioconjugation, probe development, and drug delivery.
Key Features and Benefits:
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Dual Azide Groups: Enable CuAAC and SPAAC click chemistry with alkynes.
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Thiol Group: Reacts selectively with maleimides or disulfides.
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PEG2 Spacers: Provide hydrophilicity and compact spacing.
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Multifunctional Design: Supports orthogonal conjugation strategies.
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High Purity: Ensures reproducibility in research and therapeutic applications.
Applications:
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Bioconjugation: Links biomolecules using thiol and azide chemistry.
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Drug Delivery: Facilitates multifunctional payload attachment for targeted release.
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Probe Development: Builds dual-functional probes with reversible handles.
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Synthetic Chemistry: Versatile intermediate for advanced scaffold assembly.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid oxidation of thiol groups.
This product combines dual click-ready azides with thiol functionality, making it an especially versatile reagent for multifunctional bioconjugation and advanced synthetic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
