Azido-PEG5-amine
This product is a heterobifunctional PEG linker containing a terminal azide group, a PEG5 spacer, and a primary amine. It specifically enables click chemistry with alkynes and amide coupling, offering solubility, flexibility, and dual reactivity.
Key Features and Benefits
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Azide Group: Reacts with alkynes via CuAAC or SPAAC click chemistry.
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Primary Amine: Couples with carboxyls, NHS esters, or activated linkers.
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PEG5 Spacer: Provides solubility and medium chain length.
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Dual Reactivity: Combines azide click chemistry with amine conjugation.
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High Purity: Ensures reproducibility in bioconjugation and synthesis workflows.
Applications
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Bioconjugation: Links azide- and amine-reactive biomolecules.
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Probe Development: Builds multifunctional probes with dual handles.
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Drug Delivery: Provides PEG scaffolds with orthogonal reactivity.
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Material Science: Functionalizes nanoparticles, surfaces, and polymers with dual chemistry.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged moisture exposure.
This product integrates azide click chemistry with amine reactivity in a PEG5 scaffold, specifically offering solubility, orthogonality, and multifunctionality.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
