Azido-PEG23-amine
This product is a long-chain bifunctional PEG23 linker with a terminal azide for click chemistry and a primary amine for amide coupling. The extended PEG23 spacer provides excellent solubility, flexibility, and long-range spacing, making it especially suitable for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Azide Group: Enables CuAAC or SPAAC click chemistry with alkyne partners.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
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PEG23 Spacer: Provides long hydrophilicity, reduced steric hindrance, and improved flexibility.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
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Dual Reactivity: Supports orthogonal and stepwise conjugation strategies.
Applications:
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Bioconjugation: Attach proteins, peptides, and biomolecules with extended PEG spacing.
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Click Chemistry: Bioorthogonal ligation with alkyne-containing molecules.
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Drug Delivery: PEGylated linker enhances solubility and pharmacokinetics of payloads.
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Surface Modification: Functionalizes nanoparticles, hydrogels, or polymers.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve reactivity of azide and amine groups.
This product provides dual-reactive handles and long-chain PEG spacing, making it an especially versatile tool for advanced conjugation and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
