N-Me-N-bis(PEG4-t-butyl ester)
This product is a multifunctional PEG derivative featuring a methylated tertiary amine core with two PEG4 arms terminated in acid-labile t-butyl esters. This design provides solubility, orthogonal protection, and spacing, making it especially effective in controlled synthesis, bioconjugation, and drug delivery.
Key Features and Benefits:
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Methylated Amine Core: Offers a stable branching scaffold.
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Dual t-Butyl Esters: Provide acid-labile protection for stepwise synthesis.
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PEG4 Arms: Improve solubility, flexibility, and steric accessibility.
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Orthogonal Reactivity: Supports controlled deprotection and multifunctional conjugation.
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High Purity: Ensures reproducibility in advanced workflows.
Applications:
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Bioconjugation: Builds multifunctional PEGylated conjugates with controlled handles.
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Drug Delivery: Provides PEGylated scaffolds for targeted release systems.
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Probe Development: Serves as an intermediate in diagnostic probe synthesis.
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Synthetic Chemistry: Useful in orthogonal linker and polymer design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature ester cleavage.
This product combines a tertiary amine scaffold with dual Boc-protected esters, specifically providing solubility, stability, and orthogonal control for advanced conjugation and synthesis workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
