N-Boc-Tris
This product is a protected derivative of tris(hydroxymethyl)aminomethane (Tris) containing a Boc-protected amine and three hydroxyl groups. The Boc group ensures orthogonal protection of the amine, specifically allowing selective deprotection under acidic conditions. The free hydroxyls remain available for derivatization, making this reagent an especially valuable intermediate in bioconjugation, polymer modification, and medicinal chemistry.
Key Features and Benefits
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Boc-Protected Amine: Provides orthogonal protection for controlled deprotection.
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Three Hydroxyl Groups: Offer versatile handles for derivatization.
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Compact Scaffold: Provides multifunctionality in a small, stable molecule.
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Orthogonal Reactivity: Supports stepwise functionalization strategies.
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High Purity: Produced to ≥95% purity for reproducibility.
Applications
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Bioconjugation: Serves as a multifunctional scaffold for attaching biomolecules.
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Polymer and Material Science: Introduces reactive groups into polymer systems.
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Medicinal Chemistry: Functions as an intermediate in drug design.
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Probe Development: Builds multifunctional small-molecule probes.
Storage and Handling
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Storage: Store at –20 °C in a sealed container.
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Handling: Deprotect Boc under mild acidic conditions; protect hydroxyls if required.
This product combines a protected amine with three free hydroxyl groups, making it an especially compact and versatile intermediate for synthetic and bioconjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
